Thymosin Alpha-1
A 28-amino-acid thymic peptide used clinically in some countries for immune modulation.
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✨ real molecule sketch
On your supplement label?
Thymosin Alpha-1
Wellness products may list collagen hydrolysates, copper peptides, or research compound names— we decode the jargon.
Structure (cute edition)
✨ real molecule sketch
This peptide is a short chain of about 4 amino acids—think of it as a tiny protein necklace on your label.
INCI: Thymosin Alpha-1 · ~4 amino acids in our simplified view
Research & public records
Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.
Knowledge base: protein-coding gene in the species Homo sapiens — Wikipedia
PubMed: 578 indexed papers (search PubMed)
- Thymosin α1 Augments CD8⁺ T-Cell Activation and Reverses Exhaustion In Vitro. · Asian Pacific journal of cancer prevention : APJCP
- Thymosin Alpha-1 Restores Chemotherapy-Induced Antitumor Immunity by Chaperoning a MicroRNA Ligand of TLR7 in Dendritic Cells. · Cancer research
- Peptide Therapies in Thyroid Health: Emerging Applications in Endocrine and Immune Modulation. · Integrative medicine (Encinitas, Calif.)
- IL-15 Plus Thymosin α1 Reduces Senescent Hepatic CD8(+) T Cells in Hepatocellular Carcinoma via PI3K/AKT Suppression. · Journal of gastroenterology and hepatology
- A Case Report of a Multisystemic Immune-Related Adverse Event Caused by Sintilimab in Combination With Thymosin Alpha-1. · Clinical case reports
- Zerumbone mediated CD1d inhibition suppresses epithelial to mesenchymal transition in triple negative breast cancer. · Discover oncology
- Aging and Thymosin Alpha-1. · International journal of molecular sciences
- The Immunomodulatory Activity of Thymosin Alpha 1 on Tumor Cell Lines and Distinct Immune Cell Subsets. · OncoTargets and therapy
Clinical trials: 65 studies on ClinicalTrials.gov (view search)
- First Line Bio-immunotherapy With Thymosin Alpha 1 in Patients With Sensitizing EGFR Mutation Positive Non Small Cell Lung Cancer Who Are Taking Standard of Care Therapy · UNKNOWN
- Efficacy of Galantamine to Treat Schizophrenia · TERMINATED
- Tranexamic Acid to Reduce Blood Loss in Hemorrhagic Caesarean Delivery · COMPLETED
- Open-Label Safety Study of Solriamfetol in Subjects With Binge Eating Disorder · ENROLLING_BY_INVITATION
- Assessing Diagnostics At Point-of-care for Tuberculosis · RECRUITING
- Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol · RECRUITING
- Effects of Genotype on Resting State Connectivity During Methamphetamine Administration · COMPLETED
- Thymosin Alpha 1 in the Prevention of Pancreatic Infection Following Acute Necrotizing Pancreatitis · COMPLETED
ChEMBL: THYMOSIN · max phase 3.0
What brands say it does
Thymosin alpha-1 enhances T-cell function and is approved in several countries for hepatitis B/C and as an immune adjuvant. It is not FDA-approved for general wellness, but appears in longevity and immune-support protocols. Prescription-grade products differ sharply from research peptides.
Where you’ll find it
Hospital formularies (where approved), immune clinics, and research peptide markets.
Other names you might see
Ta1
Zadaxin
Thymalfasin
Similar peptides
Educational only—not medical advice. Not prescribing or dosing guidance. Talk to your doctor before starting any peptide protocol.