Pinealon
A Russian synthetic tripeptide (Glu-Asp-Arg) marketed for brain aging and sleep—limited Western trial data.
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✨ real molecule sketch
On your supplement label?
EDR tripeptide
Wellness products may list collagen hydrolysates, copper peptides, or research compound names— we decode the jargon.
Structure (cute edition)
✨ real molecule sketch
This peptide is a short chain of about 3 amino acids—think of it as a tiny protein necklace on your label.
INCI: EDR tripeptide · ~3 amino acids in our simplified view
Research & public records
Counts and links from public databases (PubMed, ClinicalTrials.gov, Wikidata, NIH drug nomenclature). Educational only — not medical advice.
Knowledge base: chemical compound — Wikipedia
PubMed: 36 indexed papers (search PubMed)
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions. · Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews
- [Comparative analysis of different methods of geroprotective]. · Advances in gerontology = Uspekhi gerontologii
- [EFFECT OF SYNTHETIC PEPTIDES ON AGING OF PATIENTS WITH CHRONIC POLYMORBIDITY AND ORGANIC BRAIN SYNDROME OF THE CENTRAL NERVOUS SYSTEM IN REMISSION]. · Advances in gerontology = Uspekhi gerontologii
- [Pinealon and Cortexin influence on behavior and neurochemical processes in 18-month aged rats within hypoxia and hypothermia]. · Advances in gerontology = Uspekhi gerontologii
- [Regulation of content of cytokines in blood serum and of caspase-3 activity in brains of old rats in model of sharp hypoxic hypoxia with Cortexin and Pinealon]. · Advances in gerontology = Uspekhi gerontologii
- [Effect of peptide geroprotectors on the navigation system learning and caspase-3 in brain structures in rats of different age]. · Advances in gerontology = Uspekhi gerontologii
- [Neuroprotective effects of peptides bioregulators in people of various age]. · Advances in gerontology = Uspekhi gerontologii
- [Analysis of some parameters of biological age and adaptation possibilities of workers of locomotive brigades]. · Advances in gerontology = Uspekhi gerontologii
Clinical trials: 25 studies on ClinicalTrials.gov (view search)
- The Effect of Diet on Learning Abilities for Children in Kindergarden · COMPLETED
- Effects of Protein Type and Mineral Form on Amino Acid Availability · NOT_YET_RECRUITING
- Amino Acids Expression Profiling of Patients With Sepsis · UNKNOWN
- Determination of the Safety and Efficacy of Two Probiotic Strains · UNKNOWN
- Effects of Microbial Protease Supplementation on Postprandial Plasma Amino Acid Concentrations and Appetite · COMPLETED
- Immunometabolic Mechanisms of Blood Flow Restriction (BFR) Training After Anterior Cruciate Ligament Reconstruction · RECRUITING
- Traumatic Brain Injury and the Gut Microbiome · COMPLETED
- Microbial Enzyme Impact on Postprandial Nutrient Levels and Gastrointestinal Symptoms in Healthy Adults · COMPLETED
ChEMBL: MACROCYCLIC TRIPEPTIDE MOTIF
What brands say it does
Pinealon is a short bioregulatory peptide studied in Russian literature for neuroprotection and circadian regulation. Western peer-reviewed human trials are sparse. Often sold as a nasal or injectable research product with anecdotal cognitive and sleep reports.
Where you’ll find it
Longevity clinics, Russian peptide literature, and online biohacking suppliers.
Other names you might see
EDR tripeptide
Glu-Asp-Arg
Compare with similar peptides
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Educational only—not medical advice. Not prescribing or dosing guidance. Talk to your doctor before starting any peptide protocol.